CRO clinical research is fast becoming a popular lab-based career that appeals to many research experts. A CRO works directly with pharmaceutical companies and they like to speed up the drug development process and simplify things, which is a huge benefit to large companies that don’t have the necessary resources.
Drug trials can take as many as 10 years to complete, and sometimes more depending on things being overlooked. Costs continue to increase, regulations become stricter and without a reliable group of professionals, procedures can take much longer.
As independent organizations, CROs take over once the sponsor gets to a point in their process where they feel a new drug or treatment shows potential. They help in the development process by employing the right experts to test on both animals and humans as directed, and follow careful regulations to assess the new drug properly in their provided clinical setting.
They operate worldwide in order to obtain clearer results and readings, and many continue to expand their reaches and employ a wider variety of experts in order to get ahead of the competition. The more variety they offer, the better.
Who Works at a CRO?
Many of the experts employed by a CRO say their role is very rewarding. They feel as though their part however small changes the lives of millions of people. Making a difference is clearly the reason they chose their positions so obtaining a job within a CRO is a dream come true. Further, stress is at a minimum for most depending on the stage of research they are in.
Any individual considering going after a job at a CRO should have a college degree as well as relevant experience in order to be competitive. Experience in a clinical setting will help, and keeping updated on regulations is a bonus as they’ll need to do so anyway upon hire. These standards prove that a CRO is an excellent choice for pharma companies when it comes to working through all the trials quickly and accurately. On the job training comes standard as well. All this just proves why these companies are on the rise throughout the world.
The CRO to be hired should offer plenty of experience, to include industry and therapeutic expertise, delivery models, regulatory expertise, a global presence and experience with commercialization to name a few.
Setting out to find a cure for the world’s most debilitating and deadly diseases is not a small venture. Diabetes, HIV, Alzheimer’s, MS and of course Cancer are some of those that come to mind when considering those that are a threat; but of course, there are many, many more. The staff should include experts in oncology, toxicology, immunology and other experts. Having the most talented and experienced minds on staff throughout the entire industry helps them find solutions for their sponsors. Staying on course is of the utmost importance in addition to keeping up with today’s pharmaceutical industry to include regulation demands, expired patents and pricing as far as supply and demand.
Regulatory expertise is necessary to ensure the success of new drugs. Any CRO that can navigate the barriers set forth by the FDA and other regulators is a prime choice. They should be backed by integrated and advanced technologies that offer ease of filings, optimized trials and the ability to keep the trial moving forward.
Finally, a global presence means communication along with the right tools and technology will work together seamlessly to bring the product into fruition all over the world, wherever it’s needed. If a CRO has all these characteristics, the trials will run smoothly as possible.
The first thing you will find when it comes to effective couples counselling is a view on relationships and how they can change. When you first met your partner you may have been at school, you were both young and carefree. Over the years you have married and had a family and the reality of daily life has changed you and you have noticed you are growing apart. This isn’t uncommon and over time relationships do change, its how you deal with the change and what you do to keep that flame alive and live together that matters.
It is very important at this point to note that couples counselling may not be for everyone and in some instances it may have an opposite outcome to what you were hoping for. There are some couples who find that their relationship cannot go anywhere and that separating and moving on with their lives is the best thing for them and their families. While this may not be the outcome you were hoping for, it is possible that with the help of therapy you identify that it is the best course of action moving forward.
Effective couples counsellors will work with you on changing how you behave with each other. In some instances, how you interact with each other changes and this can lead to problems. Focusing on good interactions and ensuring that you always take the other person into consideration, on both sides, can help you strengthen your relationship and enjoy a fulfilling life in the future.
One of the problems you may find within your relationship, is as things have started to strain between you, you have avoided any emotional contact with each other. Avoiding emotional contact can be a dangerous and slippery slope. With effective couples counselling you will learn how to reduce emotional avoidance and how to deal with issues head on, getting it off your chest and clearing the air quickly and effectively.
A couples counsellor will work with both of you to encourage communication. Effective communication is imperative to a successful and happy relationship. You need to be open and willing to share your thoughts and feelings with your partner, even if you know what you have to say will upset them. Bottling things up is only going to result in a volatile fight later on, something you would rather avoid. Holding onto feelings results in anger, contempt and anger and you rather want to work on communicating your feelings and helping you manage your emotions each and every day.
In addition to this, you will find that with an effective couples counsellor you will learn how to strengthen your relationship. You will be given the building blocks to start making those essential repairs and learning new ways and techniques to deal with issues and come up with solutions. Every relationship requires some form of compromise on both sides, so knowing what you need to do and trusting your partner that they will make an effort is the only way to achieve success and enjoy a long term relationship moving forward.
Planning to lose weight? Dealing with high blood pressure levels? Did you get your cholesterol levels checked? If not, then do it now. Just make sure to check your triglycerides levels as they can really impact your body to a great extent. Triglycerides are probably one of the reasons why you are overweight keeping aside other factors such as family history and side effects of certain medications. If you want to know how to lower triglycerides, then here are some of the ways, not to mention a natural remedy for cholesterol called CholesLo.
What are triglycerides?
It is important for you to know what triglycerides are and how they affect your body. While limited amount of triglycerides are good for your health, some can increase the chances of getting heart diseases.
Triglycerides is a fat that is seen in your blood. Whenever you consume food, the calories are converted into triglycerides by the body and is stored in your fat cells. It is later on released when you are tired and need a quick boost of energy. But if you consume food more than you can burn especially carb or fatty foods, the level of triglycerides shoots up which can increase your health risk factors.
Just take your lipid profile test which will give you the exact range where you stand. Here are some of the normal to high range.
American Heart Association (AHA) says that maintaining a level of 100 mg/dl or low is best for keeping risk factors at bay. This would increase the health of your heart and gives you optimum benefits. All you need to do is make small lifestyle changes and you will notice a change in your body.
Triglycerides and cholesterol:
They are both different things and perform different functions in the body. While the triglycerides utilize the calories and convert them to energy for your body, the cholesterol on the other hand ‘makes’ the cells and hormones. As they don’t dissolve in the bloodstream, they keep circulating in the body and go deposit themselves in certain areas of the body.
Though there are many researches and studies going on, triglycerides may affect the arterial walls and increase the risk of heart diseases. Other diseases include heart disease, obesity, metabolic syndrome which is a combination of conditions such as excess fat in the unwanted areas, high blood pressure or sugar levels and increasing level of triglycerides and cholesterol.
Healthy tips to lower your triglycerides:
Shed that extra pounds: Starting now, target to lose excess weight. Check you BMI and make it a point to lose that abnormal fat from your body. I know the initial week will be tough but with a little persistence and patience, you can lose weight easily which will automatically lower the triglycerides level in the body. This is claimed as one of the effective and natural remedies for cholesterol.
Watch calories: Excess calories can promote cardiovascular diseases, weight gain and many more. As far as possible, keep away from sugar, salt, refined white flour and fried foods that can raise the level of triglycerides.
Limit the cholesterol intake: Do not consume more than 300 mg of cholesterol in a day. Foods such as meats, eggs, dairy products etc. contain saturated fat that can shoot up your LDL cholesterol which can be detrimental.
Fatty foods: Go with unsaturated fat that can be found in peanut, fish or plants that are healthy and can be beneficial for your life. Use replacements such as soya for meat, whole grain products for refined flour or baked goods, yogurt for cheese/butter etc. If at all you want non-vegan foods, fish (salmon, sardines, mackerel) can prove beneficial as it contains potent omega 3 fatty acids that can lower your cholesterol. Trans fat is another type of triglycerides booster that can hinder the normal functions of the body. Normally seen in baked products such as cookies, cakes etc., trans fat can really trigger the triglycerides level even if consumed in small amounts. Though the manufacturers may claim that the product contains less than 0.5 gms, it can still contribute to your weight gain. Stay away from them as a momentary craving can make you pay for you big time.
No bad habits: Cut down on your habits for smoking or drinking. These habits can add up to the stress levels of your body and can raise the level of blood pressure. This in turn can damage your liver, lungs not to mention increase the risk of heart diseases. Alcohol possess good calories that can raise the triglyceride level so even if you drink them in small amounts they can still make a difference in your body.
Pump up: A 30-60 minute of heavy workout can really make a difference in your body. Those increased heart beat, bloods pumping to the heart can be very beneficial and can lower both your triglycerides and cholesterol level. Indulge yourself in any activity that will make you lose your cholesterol level. Take some time off your busy schedule and spend some time for yourself. Even a brisk walk around your neighborhood or taking the stairs for work can really make a difference. Instead of sitting on the couch munching popcorn while watching television, doing some sit ups are also be considered as one of the natural remedies for cholesterol.
Medications for lowering triglycerides:
One of the common medications recommended by many medical practitioners for lowering triglycerides is statins. Almost 90% of the people dealing with high cholesterol pop statins every day. The benefits of statins are well known by all as apart from lowering the cholesterol level, they also control triglycerides. In fact, statin is the only cholesterol medication that can reduce the risk of getting cardio attacks or strokes. Other alternatives for cholesterol are niacin, fibrates etc.
Here comes the downside of statins. Once initiated with statins, you can’t get rid of them… ever. That’s right. Statins need to be consumed for a prolonged period or can I say, a lifetime. Another bitter fact is statins comes with its share of side effects. Some of the known side effects are digestive problems, pain in body muscles, liver damage, cataracts and many more.
“Walk-in clinic” is a loosely defined term that can encompass some non-traditional medical care facilities. The common thread, as the name suggests, is the fact that these institutions accept people who come in without an appointment. They can be urgent care facilities that treat immediate medical needs that don’t quite warrant a trip to the emergency room. Or, the term can refer to convenient care kiosks or departments housed within pre-existing businesses. An example would be a pharmacy, supermarket, shopping mall, or drug store that also provides health screening, preventive care, vaccinations, and other services. Depending on how you categorize it, community health centers may also fall within the umbrella definition of a walk-in clinic.
No matter how exactly you define it, one thing is clear: the walk-in clinic is changing the way people in the United States receive medical care and the way they interact with the medical profession. In 1995, there were less than 1,000 medical centers in the United States that didn’t require an appointment. Twenty years later, in 2015, there were nearly 11,000 such facilities. The rapid growth is mainly spurred by the twin factors of convenience and cost. First, most urgent care and retail facilities are open past five in the afternoon, and many are also open on weekends. For people who work regular nine-to-five jobs Monday through Friday, these hours are a huge advantage.
To see a traditional general practitioner, a patient ordinarily has to schedule an appointment in advance and miss part of their workday to receive care. At a walk-in clinic, a patient has a broader range of hours and can fit their visit around their schedule, rather than rearrange their schedule to accommodate the visit. Further, because many of these medical care centers are co-located with retail locations, patients can tick a few items off their shopping list while they wait. Another convenience is that a person can receive care the same day. With traditional physicians, even regular patients might have to wait weeks before they can get an appointment. For someone suffering from, for example, an ear infection, immediate diagnosis and medicine are necessary to alleviate the pain.
Cost is a more tenuous advantage since both the purpose of the visit and the level and type of insurance coverage can change the calculus. On average, a visit to a primary-care physician runs around $120 while a visit to a retail care center only costs around $75. Urgent care can be slightly more expensive than going to a clinic because they have an attendant MD on hand at all times, and doctors demand higher salaries. A study, however, showed that urgent care is still slightly less expensive when factoring in the cost of prescriptions.